Comparison of left ventricular mechanical dyssynchrony parameters between exercise and adenosine triphosphate stress tests using gated single-photon emission computed tomography myocardial perfusion imaging

Background: Left ventricular mechanical dyssynchrony (LVMD) can be induced after stress test. However, no studies have compared the influence of different stress‑inducing methods on LVMD parameters. Aims: The aim study was to determine whether there is a difference between exercise and adenosine triphosphate (ATP) tests in terms changes parameters assessed using gated single‑photon emission computed tomography myocardial perfusion imaging (GSPECT MPI). Methods: A total of190 patients who underwent 99mTc ‑sestamibi GSPECT MPI were consecutively enrolled. Treadmill ATP performed 95 each. Normal defined as summed score (SSS) ≤3 rest (SRS) ≤3, ischemia SSS >3 SRS infarction >3. Parameters LVMD, including phase standard deviation (PSD), bandwidth (PBW), skewness, kurtosis compared. Subtraction made values during phases acquire ∆PSD, ∆PBW, ∆skewness, ∆kurtosis Results: There differences groups. same results obtained normal perfusion, ischemia, subgroups. Furthermore, observed ∆PSD (median [interquartile range, IQR], 0.25 [–2.3 3.1] vs 0.42 (–1.7 3.1]; P = 0.73), ∆PBW [IQR], 1 [–7 11] [–6 11]; 0.95), ∆skewness (mean [SD], –0.06 [0.63] 0 [0.81]; 0.53), –0.47 [–4.2 4.3] –0.42 [–4.8 5.2]; 0.73) methods. Conclusions: are Thus, 2 used alternatively.